It works VERY well and has found a permanent slot in my Mac. In fact, so far I have nothing but high marks for this card. I had no bluetooth interference during large or short transfers. I've tested it pretty extensively and I can't find any negative characteristics to this card. The Inateck card for Mac easily powers 4x 7200 RPM 1TB laptop drives without any additional power requirements. Keep in mind however that the 1144CM can't handle most of the devices I listed above, it only works with storage devices. Plugging in multiple drives does slow it slightly, giving the 1144CM the edge for raw storage speed where multiple drives are installed. I transferred hundreds of GB of data to and from a mechanical USB 3.0 drive and it's just as fast as the 1144CM with a single drive. It has no conflicts with any of my other hardware (including the installed HighPoint 1144CM).
This card is easily installed, and works immediately with the OS X built in drivers. The card preforms well and had no problems recognizing more than 1 dozen devices I tried (web cams, keyboard, mice, printers, scanners, belkin hub, thumb drives, portable USB drives etc…) I only did a few quick tests which are in no way comprehensive, but here's my take on it. Still recovering from major surgery, I did get up today and decided to remove the Orico 2P card and install the new Inateck KT4004 4-Port USB 3.0 PCI-E Express Card for Mac in my 5.1 system.